Comprehensive Review

The Importance of Selenium Before, During, and After Pregnancy

The risk of two important adverse outcomes of pregnancy—preterm birth and preeclampsia—may be selenium responsive. Pregnancy is a dynamic process characterized by an apparent increase in maternal utilization of selenium. Without supplementation, blood levels of selenium progressively decline during pregnancy and lactation. Inadequate selenium status in infants may enhance their vulnerability to adverse health outcomes, including bacterial infection (sepsis), impaired neurological development, and autism.

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