Zinc Bisglycinate

Fully-Reacted Chelated Mineral

Zinc bisglycinate, a chelated form of zinc, has been shown to have improved absorption and bioavailability compared to other forms of zinc. [i]

Zinc bisglycinate and zinc glycinate refer to the same mineral. Zinc bisglycinate is the chemical or scientific name of this form of zinc.

The zinc bisglycinate produced by Cypress Ingredients is fully chelated, which increases its bioavailability in the body. Fully reacted, chelated minerals remain covalently bonded and can be properly absorbed and used by the body. Additionally they do not disassociate in the stomach’s acidic environment.

Fully reacted mineral ingredients, such as our zinc bisglycinate are up to four times more bioavailable, with less inhibition by other minerals, and have fewer potential side effects.


What is Zinc Bisglycinate?


Zinc bisglycinate is chelated or bound to two glycine molecules. The chelation process improves the absorption and bioavailability of the mineral.

Because zinc bisglycinate is more readily absorbed and easier on the digestive system than other forms of zinc, it is a popular ingredient in supplements. 1 ‡

Zinc Bisglycinate Research Data

Research on zinc bisglycinate and zinc highlights potential positive health outcomes: 1, 5, 6, 7, ‡

A bioavailability study involving 12 healthy female volunteers yielded positive results for zinc bisglycinate in a comparison between zinc bisglycinate and zinc glycinate. The study results showed increased oral bioavailability of zinc bisglycinate was 43.4% higher than zinc gluconate.

A review of randomized controlled trials concluded that zinc supplementation may maintain healthy blood sugar already within normal range.

A comparative study of 30 healthy females monitoring absorption of zinc bisglycinate and zinc gluconate for six weeks, showed people in the zinc bisglycinate group had on average higher zinc blood levels.

Some research suggests that zinc supplementation may positively impact health and wellness in young adults.

Recommended Daily Allowance of Zinc

Males aged 19+: 11 mg

Females aged 19+: 8 mg

Females aged 19+ who are pregnant: 11 mg

Females aged 19+ who are breast feeding: 12 mg

Applications for Zinc Bisglycinate

Supplement Capsules on Black 200-2



Supplement Application Gummies on Black 200



Blue tablets pills flu doctor antibiotic pharmacy medicine medical in a bottle on blue wood background



Chocolate bars with nuts filling on black table.


Foods &

Benefits of Zinc Bisglycinate

The potential benefits of zinc bisglycinate and zinc may include: 2, 3, 4, 8, ‡

Providing immune system function support.

Supporting fetal, infant, childhood, and adolescence growth and development.

Digestive support

Supports DNA and bone production

Involved in sense of smell and taste.

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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

1 Gandia P, Bour D, Maurette JM, Donazzolo Y, Duchène P, Béjot M, Houin G. A bioavailability study comparing two oral formulations containing zinc (Zn bis-glycinate vs. Zn gluconate) after a single administration to twelve healthy female volunteers. Int J Vitam Nutr Res. 2007 Jul;77(4):243-8. doi: 10.1024/0300-9831.77.4.243. PMID: 18271278. (Accessed July 21, 2023) https://pubmed.ncbi.nlm.nih.gov/18271278/

2 Zinc: Mount Sinai (Accessed July 21, 2023) https://www.mountsinai.org/health-library/supplement/zinc

3 Zinc: Fact Sheet for Health Professionals (Accessed July 21, 2023) https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/

4 Zinc: Harvard T.H. Chan School of Public Health (Accessed July 21, 2023) https://www.hsph.harvard.edu/nutritionsource/zinc/

5 Xinhui Wang and others, The American Journal of Clinical Nutrition, Volume 110, Issue 1, July 2019, Pages 76–90. (Accessed July 21, 2023)  https://doi.org/10.1093/ajcn/nqz041

6 DiSilvestro RA, Koch E, Rakes L. Moderately High Dose Zinc Gluconate or Zinc Glycinate: Effects on Plasma Zinc and Erythrocyte Superoxide Dismutase Activities in Young Adult Women. Biol Trace Elem Res. 2015 Nov;168(1):11-4. doi: 10.1007/s12011-015-0334-3. Epub 2015 Apr 17. PMID: 25877802. (Accessed July 21, 2023) https://pubmed.ncbi.nlm.nih.gov/25877802/

7 Kim J, Ahn J. Biol Trace Elem Res. 2014 Feb;157(2):101-6. doi: 10.1007/s12011-013-9885-3. Epub 2014 Jan 10. PMID: 24402636. (Accessed July 21, 2023) https://pubmed.ncbi.nlm.nih.gov/24402636/

8 What is Chelated Zinc and What Does It Do? (Accessed July 23, 2023) https://www.healthline.com/health/chelated-zinc